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Insight into Single-Molecule Imaging Techniques for the Study of Prokaryotic Genome Maintenance
Genome maintenance comprises a group of complex and interrelated processes crucial for preserving and safeguarding genetic information …
Nischal Sharma
,
Antoine Van Oijen
,
Lisanne Spenkelink
,
Stefan Mueller
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Development of a generalisable tryptophan-optimised quenchbody biosensor based on a synthetic nanobody library
Quenchbodies are antibodies labelled with a fluorophore that increases in intensity upon antigen binding, which makes them promising …
Jordan Cater
,
Nehad El Salamouni
,
Ghada Mansour
,
Sebastian Hutchinson
,
Conall Mc Guinness
,
Stefan Mueller
,
Richard Spinks
,
Nirukshan Shanmugam
,
Adeline Pichard-Kostuch
,
Viktor Zahoransky
,
Harshad Ghodke
,
Marco Ribezzi-Crivellari
,
Haibo Yu
,
Antoine Van Oijen
,
Andrew Griffiths
,
Lisanne Spenkelink
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Embracing Heterogeneity: Challenging the Paradigm of Replisomes as Deterministic Machines
The paradigm of cellular systems as deterministic machines has long guided our understanding of biology. Advancements in technology and …
Jacob Lewis
,
Antoine Van Oijen
,
Lisanne Spenkelink
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