DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies

Abstract

The replicative helicase is a key component of the replisome that unwinds duplex DNA to provide the single-stranded DNA template for DNA polymerases. Using single-molecule fluorescence imaging, this study investigates the dynamics of the Escherichia coli DnaB helicase during DNA replication.

Publication
Nucleic Acids Research